Abstract: In order to realize ventilation air methane in coal mine recycling, the vacuum pressure swing adsorption technology was adopted. The single factor experiment and orthogonal experiment were carried out in view of the variable experimental parameters in the pressure swing adsorption system. The influences of desorption pressure, feed gas concentration and the height to diameter ratio of adsorption tower were analyzed. The experimental results show that the volume fraction of desorption methane gas is higher with the lower of the desorption pressure, and the lifting ratio is smaller with the higher of the feed methane gas. The influence of different factors has an order: desorption pressure > feed methane gas > lifting ratio. The best experimental working parameters are desorption pressure of 0 kPa, and methane volume fraction of feed methane gas of 0.1%, and the height to diameter ratio of adsorption tower of 10.33, and the biggest lifting ratio of 1.68.