Abstract: To study the layout of the short-distance thick underlying coal seam stopping roadway in Yanzishan Mine, a mechanical model of the remaining coal pillars in 4216 and 4218 of No. 4 sides of the overlying coal seam through theoretical calculation, and clarified the transfer law of the principal stress difference of the remaining coal pillars in the floor. The author simulated the distribution characteristics of vertical stress, horizontal stress and difference between principal stresses at different depths of floor by using FLAC^3D numerical software, and analyzeds the principal stress difference and the stress reducing area roadway within the reasonable factors that influence of the reasonable inner distance. The results show that the roadway layout should avoid the peakand be in the environment of principal stress difference. When the horizontal distance of the lower coal seam is more than 30 m from the edge of the overlying coal pillar, the vertical stress is close to the original rock stress, the average principal stress difference is less than 1.24 MPa, and the principal stress difference change rate is low. Finally, the mining roadway of the working face of the lower coal seam is arranged with an inner stagger distance of 30 m. The field practice shows that the deformation of the surrounding rock is small under the misspacing, which can ensure the safety and efficient production of the mine.